Monday, August 18, 2014

VIZYLAC CAPSULE


(10 Capsules in Strip)
Unichem Laboratories Ltd
Rs. 2.17 / Capsule
Rs.21.75

Composition
Pyridoxine (0.75mg),Riboflavin (2.5mg),D-Panthenol (2.5mg),Thiamine(2.5 mg),Nicotinic Acid (22.5 mg)
Pyridoxine (0.75mg)

INDICATORS
Pregnancy:B Lactation:L2 Lab:NA Food:NA

 USAGE
Anaemia, Deficiency states, Idiopathic sideroblastic anaemia, Isoniazid neuropathy, Oedema and ascites in cirrhosis of the liver, Premenstrual syndrome, Schizophrenia and other psychoses, Vitamin deficiency.

SIDE EFFECTS
Dizziness, Drowsiness, Blurred vision, Pain, Burning.

DRUG INTERACTION
None mentioned.

MECHANISM OF ACTION

Vitamin B6 is the collective term for a group of three related compounds, pyridoxine (PN), pyridoxal (PL) and pyridoxamine (PM), and their phosphorylated derivatives, pyridoxine 5'-phosphate (PNP), pyridoxal 5'-phosphate (PLP) and pyridoxamine 5'-phosphate (PMP). Although all six of these compounds should technically be referred to as vitamin B6, the term vitamin B6 is commonly used interchangeably with just one of them, pyridoxine. Vitamin B6, principally in its biologically active coenzyme form pyridoxal 5'-phosphate, is involved in a wide range of biochemical reactions, including the metabolism of amino acids and glycogen, the synthesis of nucleic acids, hemogloblin, sphingomyelin and other sphingolipids, and the synthesis of the neurotransmitters serotonin, dopamine, norepinephrine and gamma-aminobutyric acid (GABA).


Riboflavin (2.5mg)
INDICATORS
Pregnancy:A Lactation:L2 Lab:NA Food:NA

TYPICAL USAGE - Arabinoflavinosis, Vitamin deficiency.

SIDE EFFECTS - Discoloration of urine, Swelling of face, Difficulty breathing, Swelling of lips and tongue.

DRUG INTERACTION - Arabinoflavinosis, Vitamin deficiency.

MECHANISM OF ACTION
Binds to riboflavin hydrogenase, riboflavin kinase, and riboflavin synthase. Riboflavin is the precursor of flavin mononucleotide (FMN, riboflavin monophosphate) and flavin adenine dinucleotide (FAD). The antioxidant activity of riboflavin is principally derived from its role as a precursor of FAD and the role of this cofactor in the production of the antioxidant reduced glutathione. Reduced glutathione is the cofactor of the selenium-containing glutathione peroxidases among other things. The glutathione peroxidases are major antioxidant enzymes. Reduced glutathione is generated by the FAD-containing enzyme glutathione reductase.


D-Panthenol (2.5mg)

INDICATORS - Pregnancy:A Lactation:L1 Lab:NA Food:NA


Thiamine(2.5 Mg)

INDICATORS - Pregnancy:C Lactation:L3 Lab:NA Food:NA

TYPICAL USAGE
Lung cancer and pancreatic cancer, mild chronic deficiency, severe deficiency, thiamine deficiency prophylaxis, thiamine deficiency treatment.

SIDE EFFECTS
Nausea, urticaria, Gi bleeding, angioneurotic edema, restlessness, pruritis, pulmonary edema, hemorrhage, cyanosis,

DRUG INTERACTION
Thiamine is known to interact with other drugs like aluminium hydroxide and oxide, amiloride (HCl), bumetanide, chlorthalidone, estradiol (Valerate), estrogens conjugated, fluorouracil, magnesium carbonate, magnesium oxides and hydroxides, metformin (HCl), phenobarbital Sodium, phenobarbitone, triamterene, vecuronium (Br). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION
Thiamine is mainly the transport form of the vitamin, while the active forms are phosphorylated thiamine derivatives. There are five known natural thiamine phosphate derivatives: thiamine monophosphate (ThMP), thiamine diphosphate (ThDP), also sometimes called thiamine pyrophosphate (TPP), thiamine triphosphate (ThTP), and the recently discovered adenosine thiamine triphosphate (AThTP), and adenosine thiamine diphosphate. Each derivative has unique functions, however, most are involved as coenzymes.


Nicotinic Acid (22.5 Mg)

INDICATORS - Pregnancy:C Lactation:L5 Lab:NA Food:NA

TYPICAL USAGE - Treatment of nicotine dependence, as an aid to smoking cessation.

SIDE EFFECTS
Urticaria, cramps, myalgia, blurred vision, acanthosis nigricans, ichthyosis, toxic amblyopia, atrial arrhythmias, elevated serum aspartate transaminase, hepatitis, hepatic failure, flushing, headache, pruritus, diarrhea, gastric irritation, flushing, bloating.

DRUG INTERACTION
Nicotinic Acid is known to interact with other drugs like alcohol, atorvastatin, colestipol (HCl), fluvastatin, glibornuride, gliquidone, technetium Tc-99m disofenin, technetium Tc-99m lidofenin. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

MECHANISM OF ACTION
Nicotinic acid is a derivative of vitamin B and is incorporated into coenzymes nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), which are involved in multiple cellular metabolic pathways. Nicotinic acid also reduces total serum cholesterol, LDL, VLDL, and triglycerides, and increases HDL cholesterol. It appears to decrease hepatic synthesis of VLDL.

No comments:

Post a Comment