Sunday, February 24, 2013

CAMYLOFIN


Camylofin is an antimuscarinic.
It is used to treat stomach ache in infants and children. Usually it is given in combination with paracetamol to treat stomach ache, as well as Pyrexia.


IUPAC NAME -
isopentyl 2-[2-(diethylamino)ethylamino]-2-phenylacetate

INDICATION & DOSE --- Parenteral
Intestinal colic, Biliary colic, Renal colic, Dysmenorrhoea
Adult: 1mL (25 mg) by IM or IV Inj up to a max of tid


Contraindications -Narrow-angle glaucoma, prostatic hypertrophy, mechanical stenoses.

Special Precautions Camylofin Inj must be administered with care in thyrotoxicosis, obstructive airway disease, during cardiac surgery, elderly or those with fever.


Adverse Drug Reactions - Injection may cause skin rashes, other allergic reactions and infrequently atropine-like side effects.

Drug Interactions - Camylofin Inj should be co-administered with caution in patients taking amantadine, quinidine and tricyclic antidepressants



Mechanism of Action - Camylofin is a smooth muscle relaxant with both anticholinergic action as well as direct smooth muscle action. Anticholinergic action is produced by inhibiting the binding of acetylcholine to muscarinic receptors, but the action is less pronounced. Direct smooth muscle relaxation is achieved by inhibiting phosphodiesterase type IV, which leads to increased cyclic AMP and eventually reduced cytosolic calcium. Thus camylofin has a comprehensive action to relieve smooth muscle spasm.

ATC Classification  - A03AA03 - camylofin ; Belongs to the class of synthetic anticholinergics, esters with tertiary amino group. Used in the treatment of functional bowel disorders.



China - 1 Results
卡米罗芬/camylofin
India - 7 Results
ANAFORTAN  [ Khandelwal ]
ANAFORTAN SYR  [ Khandelwal ]  Interaction
ANAFORTAN TAB  [ Khandelwal ]  Interaction
ANAFORTAN-N  [ Khandelwal ]  Interaction
ANASPAS  [ Khandelwal ]  Interaction
camylofin
SUMO-SPAS  [ Alkem ]  Interaction

Indonesia -
camylofin

Hong Kong -
camylofin

Malaysia - 1 Results
camylofin

Philippines - 1 Results
camylofin

Singapore - 1 Results
camylofin

Thailand -
camylofin

Vietnam - 0 Results

USA - 1 Results


No comments:

Post a Comment