Celiprolol is a medication in the class of beta blockers, used in the treatment of high blood pressure. It has a unique pharmacology: it is a selective β1 receptor antagonist, but a β2 receptor partial agonist. It is also a weak α2 receptor antagonist.
A recent clinical trial has suggested a use for this medication in the prevention of vascular complications of a rare inherited disease called vascular Ehlers–Danlos syndrome. This study demonstrated decreased incidence of arterial rupture or dissection (a specific type of arterial rupture in which the layers of the vessel separate prior to complete failure of the artery wall)
Brand names - Cardem, Selectol, Celipres, Celipro, Celol, Cordiax, Dilanorm
Before taking celiprolol
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking celiprolol it is important that your doctor or pharmacist knows:
If you are pregnant, trying for a baby or breast-feeding.
If you have liver or kidney problems.
If you have low blood pressure or poor circulation.
If you have asthma or breathing difficulties.
If you have sugar diabetes.
If you have psoriasis (a skin problem).
If you have myasthenia gravis (a condition causing muscle weakness).
If you have been told you have a slow heartbeat or heart block (a slow and irregular heartbeat).
If you have been told you have Prinzmetal's angina (chest pain caused by spasms of the heart's blood vessels).
If you have phaeochromocytoma (a tumour on your adrenal gland).
If you are taking other medicines, including those available to buy without a prescription, herbal and complementary medicines.
If you have ever had an allergic reaction to a medicine, or if you have ever had any other severe allergic reaction.
How to take celiprolol
Before you start this treatment, read the manufacturer's printed information leaflet from inside the pack. The leaflet will give you more information about celiprolol and a full list of side-effects which you may experience from taking it.
Take celiprolol exactly as your doctor has told you. There are two strengths of tablet - 200 mg and 400 mg. It is usual to start by taking one 200 mg tablet daily, although your doctor may later increase this to the 400 mg strength tablet. You should take the tablet first thing in the morning, preferably 'on an empty stomach'. This means that you should take it at least 30 minutes before breakfast or wait until two hours afterwards. Swallow the tablet with a drink of water.
If you forget to take a dose, take it when you remember. (If possible, remember to take it half an hour before a meal, or two hours after a meal). If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.
Getting the most from your treatment
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress.
It is very important to follow any dietary and lifestyle advice that you may have been given by your doctor, such as eating a healthy diet, not smoking, and taking regular exercise.
If you drink alcohol, ask your doctor for advice about taking celiprolol and alcohol. Alcohol will add to the blood pressure lowering effect of celiprolol and so may not be recommended for you.
If you have diabetes, celiprolol may block the symptoms of low blood sugar. Your doctor will be able to advise you about this.
If you are having an operation or dental treatment, tell the person carrying out the treatment that you are taking a beta-blocker.
Treatment with celiprolol is usually long-term so continue to take these tablets unless your doctor tells you to stop. Stopping treatment suddenly can cause problems in some people, so your doctor will probably want you to reduce your dose gradually if this is necessary.
If you buy any medicines, check with a pharmacist that they are suitable for someone with high blood pressure to take. Some medicines (including some cough, cold and flu remedies) may not be.
How to store celiprolol
Keep all medicines out of the reach and sight of children.
Store in a cool, dry place, away from direct heat and light
Taking other medicines
If you are taking more than one medicine they may interact with each other. At times your prescriber may decide to use medicines that interact, in other cases this may not be appropriate.
The decision to use medicines that interact depends on your specific circumstances. Your prescriber may decide to use medicines that interact, if it is believed that the benefits of taking the medicines together outweigh the risks. In such cases, it may be necessary to alter your dose or monitor you more closely.
Tell your prescriber the names of all the medicines that you are taking so that they can consider all possible interactions. This includes all the medicines which have been prescribed by your GP, hospital doctor, dentist, nurse, health visitor, midwife or pharmacist. You must also tell your prescriber about medicines which you have bought over the counter without prescriptions.
The following medicines may interact with Celiprolol hydrochloride:
The following types of medicine may interact with Celiprolol hydrochloride:
calcium channel blockers
monoamine oxidase inhibitors
prostaglandin synthetase inhibitors
Post a Comment