FURAZOLIDONE

Furazolidone is a nitrofuran antibacterial. It is marketed by Roberts Laboratories under the brand name Furoxone and by GlaxoSmithKline

3-{[(5-nitro-2-furyl)methylene]amino}-1,3-oxazolidin-2-one

Uses
Furazolidone has been used in human and veterinary medicine. It has a broad spectrum of activity being active against

Gram positive
Clostridium perfringens
Corynebacterium pyogenes
Streptococci
Staphylococci


Gram negative
E coli
Salmonella dublin
Salmonella typhimurium


Protozoa
Giardia lamblia
Eimeria species
Histomonas meleagridis

Giardiasis, Cholera
Adult: 100 mg 4 times daily. Usual duration: 2-5 days, up to 7 days in some patients or 10 days for giardiasis.
Child: 1.25 mg/kg 4 times daily, usually given for 2-5 days or up to 10 days for giardiasis.


Use in animals
As a veterinary medicine, furazolidone has been used with some success to treat salmonids for Myxobolus cerebralis infections.
It has also been used in aquaculture.

Use in laboratory
It is used to differentiate micrococci and staphylococci.